The team announced Monday that Fisher ruptured an Achilles tendon last week while training, and he underwent surgery Thursday. The recovery period is expected to last four to six months, meaning Fisher is likely to miss at least 20 games in the 2014-15 season.
General manager David Poile told the Tennessean, "I hope we have enough depth. We will give certain guys a chance to be successful and give Mike a chance to get back."
Fisher, 34, posted a career-high 29 assists last season, and he added 20 goals. It was his sixth campaign with at least 20 goals.
The Predators' alternate captain is halfway through a two-year, $8 million contract.
Nashville did not land a center in recent days despite making runs at Jason Spezza, Ryan Kesler and Paul Stastny, the Tennessean reported. Spezza was dealt from the Ottawa Senators to the Dallas Stars, and Kesler was traded from the Vancouver Canucks to the Anaheim Ducks. Stastny, formerly of the Colorado Avalanche, signed a four-year, $28 million free agent deal with the St. Louis Blues.
"We're not going to sign a player for the sake of signing," Poile told the Tennessean about replacing Fisher. "It has to be a fit."